guaB_2 protein (Methanobrevibacter filiformis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

guaB_2

Inosine-5'-monophosphate dehydrogenase. (273 aa)

Predicted Functional Partners:

hrp1

0.890

rpsI

0.886

rplM

0.886

impdh_3

0.818

era

0.696

pdhD

0.665

rpsL

0.642

rpsB

0.630

rplD

0.629

rplC

0.611

Your Current Organism:

Methanobrevibacter filiformis

NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
era	guaB_2	MBFIL_17250	MBFIL_11680	GTPase Era.	Inosine-5'-monophosphate dehydrogenase.	0.696
era	hrp1	MBFIL_17250	MBFIL_11670	GTPase Era.	Hypoxic response protein 1.	0.811
era	impdh_3	MBFIL_17250	MBFIL_10350	GTPase Era.	Inosine-5'-monophosphate dehydrogenase.	0.654
era	pdhD	MBFIL_17250	MBFIL_03090	GTPase Era.	Dihydrolipoyl dehydrogenase.	0.444
era	rplC	MBFIL_17250	MBFIL_16330	GTPase Era.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.548
era	rplM	MBFIL_17250	MBFIL_14030	GTPase Era.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.803
era	rpsB	MBFIL_17250	MBFIL_11090	GTPase Era.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.572
era	rpsI	MBFIL_17250	MBFIL_14020	GTPase Era.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.803
era	rpsL	MBFIL_17250	MBFIL_04820	GTPase Era.	30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	0.525
guaB_2	era	MBFIL_11680	MBFIL_17250	Inosine-5'-monophosphate dehydrogenase.	GTPase Era.	0.696
guaB_2	hrp1	MBFIL_11680	MBFIL_11670	Inosine-5'-monophosphate dehydrogenase.	Hypoxic response protein 1.	0.890
guaB_2	impdh_3	MBFIL_11680	MBFIL_10350	Inosine-5'-monophosphate dehydrogenase.	Inosine-5'-monophosphate dehydrogenase.	0.818
guaB_2	pdhD	MBFIL_11680	MBFIL_03090	Inosine-5'-monophosphate dehydrogenase.	Dihydrolipoyl dehydrogenase.	0.665
guaB_2	rplC	MBFIL_11680	MBFIL_16330	Inosine-5'-monophosphate dehydrogenase.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.611
guaB_2	rplD	MBFIL_11680	MBFIL_16340	Inosine-5'-monophosphate dehydrogenase.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.629
guaB_2	rplM	MBFIL_11680	MBFIL_14030	Inosine-5'-monophosphate dehydrogenase.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.886
guaB_2	rpsB	MBFIL_11680	MBFIL_11090	Inosine-5'-monophosphate dehydrogenase.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.630
guaB_2	rpsI	MBFIL_11680	MBFIL_14020	Inosine-5'-monophosphate dehydrogenase.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.886
guaB_2	rpsL	MBFIL_11680	MBFIL_04820	Inosine-5'-monophosphate dehydrogenase.	30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	0.642
hrp1	era	MBFIL_11670	MBFIL_17250	Hypoxic response protein 1.	GTPase Era.	0.811