Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
coaBCCoenzyme A biosynthesis bifunctional protein CoaBC. (387 aa)    
Predicted Functional Partners:
KZX17176.1
Hypothetical protein.
 
  
 0.982
patA
Putative N-acetyl-LL-diaminopimelate aminotransferase.
 
 0.941
hldE_2
Bifunctional protein HldE; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family.
    
 0.913
cysK1
O-acetylserine sulfhydrylase.
    
 0.907
aspC
Aspartate aminotransferase.
  
  
  0.885
metC
Cystathionine beta-lyase.
   
 
  0.785
thrB_2
Homoserine kinase.
 
   
 0.774
KZX16940.1
peptidyl-tRNA hydrolase.
     
 0.757
coaE
dephospho-CoA kinase.
   
 0.668
pdhD
Dihydrolipoyl dehydrogenase.
 
  
 0.602
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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