Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ndhI_6NAD(P)H-quinone oxidoreductase subunit I, chloroplastic; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (776 aa)    
Predicted Functional Partners:
lutA_1
Lactate utilization protein A.
 
 0.997
lutA_2
Lactate utilization protein A.
 
 0.995
KZX11758.1
Succinate dehydrogenase/fumarate reductase iron-sulfur subunit.
 
 0.994
KZX12225.1
Hypothetical protein.
 
 0.993
ndhI_7
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
    
  0.936
KZX17211.1
Methyl-viologen-reducing hydrogenase, delta subunit.
 
0.932
KZX11644.1
Hypothetical protein; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
   
 
 0.930
KZX11640.1
Hypothetical protein; Methyl-coenzyme M reductase beta subunit, C-terminal domain.
   
 
 0.923
KZX11643.1
Methyl-coenzyme M reductase gamma subunit.
   
 
 0.920
KZX11642.1
Methyl-coenzyme M reductase operon protein C.
   
 
 0.918
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.