Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KZX12060.1Hypothetical protein. (279 aa)    
Predicted Functional Partners:
KZX11644.1
Hypothetical protein; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
     0.756
KZX11640.1
Hypothetical protein; Methyl-coenzyme M reductase beta subunit, C-terminal domain.
  
     0.755
KZX10089.1
Hypothetical protein.
  
     0.754
KZX17300.1
Methyl-coenzyme M reductase operon protein C.
 
     0.752
KZX11642.1
Methyl-coenzyme M reductase operon protein C.
  
     0.749
KZX11643.1
Methyl-coenzyme M reductase gamma subunit.
  
     0.749
KZX10091.1
Hypothetical protein.
 
     0.748
nifD_1
Nitrogenase molybdenum-iron protein alpha chain.
  
     0.743
metN2
Methionine import ATP-binding protein MetN 2.
  
     0.742
KZX10088.1
Hypothetical protein.
  
     0.741
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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