Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
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Co-expression
Experiments
Databases
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[Homology]
Score
KZX12026.1Hypothetical protein. (349 aa)    
Predicted Functional Partners:
KZX12027.1
Hypothetical protein.
       0.854
KZX15362.1
Zc3h12a-like ribonuclease NYN domain protein.
  
     0.734
KZX17236.1
Sortase family protein.
  
     0.712
murD_2
UDP-N-acetylmuramoylalanine--D-glutamate ligase.
  
  
  0.702
mobA_2
Molybdenum cofactor guanylyltransferase.
  
     0.669
purQ
Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
     
  0.662
KZX15402.1
Pseudomurein-binding repeat protein.
  
     0.647
KZX12576.1
Transcriptional regulator PhoU.
  
     0.631
KZX10712.1
Hypothetical protein.
  
     0.623
KZX15738.1
Succinylglutamate desuccinylase / aspartoacylase family protein.
  
     0.619
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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