Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
murD_1UDP-N-acetylmuramoylalanine--D-glutamate ligase. (1086 aa)    
Predicted Functional Partners:
murD_2
UDP-N-acetylmuramoylalanine--D-glutamate ligase.
 
     0.788
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase.
 
   
 0.697
KZX12026.1
Hypothetical protein.
  
     0.575
cobQ_2
Cobyric acid synthase.
 
  
 0.569
KZX17236.1
Sortase family protein.
  
     0.557
KZX15362.1
Zc3h12a-like ribonuclease NYN domain protein.
  
     0.539
thyA
Thymidylate synthase.
  
  
  0.515
aspC
Aspartate aminotransferase.
  
     0.464
cobQ_1
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
    
 0.451
mptD
Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
     
  0.445
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.