rplA protein (Methanobrevibacter filiformis)

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query proteins and first shell of interactors

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second shell of interactors

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Score

rplA

50S ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa)

Predicted Functional Partners:

rpsI

0.999

rplM

0.999

rplK

0.999

rplJ

0.999

rpl12

0.998

rpl18a

0.997

rplN

0.997

rplF

0.997

rplR

0.997

rpl30e

0.996

Your Current Organism:

Methanobrevibacter filiformis

NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
rpl12	rpl18a	MBFIL_14690	MBFIL_05470	50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.	50S ribosomal protein LX.	0.988
rpl12	rpl30e	MBFIL_14690	MBFIL_04860	50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.	50S ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family.	0.994
rpl12	rplA	MBFIL_14690	MBFIL_14670	50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.	50S ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release.	0.998
rpl12	rplF	MBFIL_14690	MBFIL_16490	50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.	50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.	0.981
rpl12	rplJ	MBFIL_14690	MBFIL_14680	50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.	50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	0.999
rpl12	rplK	MBFIL_14690	MBFIL_14660	50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.	50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.	0.995
rpl12	rplM	MBFIL_14690	MBFIL_14030	50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.999
rpl12	rplN	MBFIL_14690	MBFIL_16440	50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.	50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.985
rpl12	rplR	MBFIL_14690	MBFIL_16520	50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.	50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	0.995
rpl12	rpsI	MBFIL_14690	MBFIL_14020	50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.999
rpl18a	rpl12	MBFIL_05470	MBFIL_14690	50S ribosomal protein LX.	50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.	0.988
rpl18a	rpl30e	MBFIL_05470	MBFIL_04860	50S ribosomal protein LX.	50S ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family.	0.996
rpl18a	rplA	MBFIL_05470	MBFIL_14670	50S ribosomal protein LX.	50S ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release.	0.997
rpl18a	rplF	MBFIL_05470	MBFIL_16490	50S ribosomal protein LX.	50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.	0.992
rpl18a	rplJ	MBFIL_05470	MBFIL_14680	50S ribosomal protein LX.	50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	0.994
rpl18a	rplK	MBFIL_05470	MBFIL_14660	50S ribosomal protein LX.	50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.	0.996
rpl18a	rplM	MBFIL_05470	MBFIL_14030	50S ribosomal protein LX.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.999
rpl18a	rplN	MBFIL_05470	MBFIL_16440	50S ribosomal protein LX.	50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.995
rpl18a	rplR	MBFIL_05470	MBFIL_16520	50S ribosomal protein LX.	50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.	0.995
rpl18a	rpsI	MBFIL_05470	MBFIL_14020	50S ribosomal protein LX.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.999