Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
pdaDPyruvoyl-dependent arginine decarboxylase. (147 aa)    
Predicted Functional Partners:
speB
Agmatinase; Belongs to the arginase family.
 
  
 0.970
argH1
Argininosuccinate lyase 1.
     
  0.936
murC_1
UDP-N-acetylmuramate--L-alanine ligase.
 
     0.796
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
     0.778
cadA
Putative cadmium-transporting ATPase.
      
 0.629
KZX14110.1
Hydroxymethylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
      
 0.592
leuS
leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
   0.541
KZX12173.1
Hypothetical protein.
  
     0.510
efp
Elongation factor P; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
  
 0.485
wcaJ
UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase.
       0.474
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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