STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ribH_26,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (138 aa)    
Predicted Functional Partners:
ribH_1
6,7-dimethyl-8-ribityllumazine synthase.
 
  
 0.992
ribD2
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase.
 
 
 0.968
KZX10971.1
Hypothetical protein.
       0.909
hldE_1
Bifunctional protein HldE; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
 
   
 0.898
nhaP
K(+)/H(+) antiporter NhaP.
  
  
 0.882
rpsI
30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
    0.771
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
    0.771
pyrB
Aspartate carbamoyltransferase.
  
    0.743
pyrD_2
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
  
  
 0.736
KZX16208.1
Serine-pyruvate aminotransferase.
     
 0.733
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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