Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cutADivalent-cation tolerance protein CutA. (110 aa)    
Predicted Functional Partners:
dfx
Desulfoferrodoxin.
  
    0.526
impdh_3
Inosine-5'-monophosphate dehydrogenase.
  
   0.497
hrp1
Hypoxic response protein 1.
  
   0.497
guaB_2
Inosine-5'-monophosphate dehydrogenase.
  
   0.497
guaB_3
Inosine-5'-monophosphate dehydrogenase.
  
   0.497
KZX10271.1
Inosine 5'-monophosphate dehydrogenase.
  
   0.497
KZX11993.1
Peptidase family M50.
       0.493
KZX17579.1
aspartyl/glutamyl-tRNA amidotransferase subunit C.
       0.484
KZX10819.1
Hypothetical protein.
       0.469
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
       0.441
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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