cas2 protein (Methanobrevibacter filiformis)

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cas2

CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (94 aa)

Predicted Functional Partners:

cas4-cas1

0.987

KZX17621.1

0.862

KZX15869.1

0.809

KZX15378.1

0.761

KZX11907.1

0.761

ubiC

0.596

KZX11909.1

0.516

KZX11452.1

0.488

KZX15390.1

0.469

vapC_1

0.466

Your Current Organism:

Methanobrevibacter filiformis

NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KZX11452.1	KZX15869.1	MBFIL_14550	MBFIL_05810	Hypothetical protein.	PD-(D/E)XK nuclease superfamily protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.	0.428
KZX11452.1	KZX17621.1	MBFIL_14550	MBFIL_00310	Hypothetical protein.	Hypothetical protein.	0.450
KZX11452.1	cas2	MBFIL_14550	MBFIL_18010	Hypothetical protein.	CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.488
KZX11452.1	vapC_1	MBFIL_14550	MBFIL_00300	Hypothetical protein.	tRNA(fMet)-specific endonuclease VapC.	0.572
KZX11907.1	cas2	MBFIL_12980	MBFIL_18010	PD-(D/E)XK nuclease superfamily protein.	CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.761
KZX11907.1	cas4-cas1	MBFIL_12980	MBFIL_18020	PD-(D/E)XK nuclease superfamily protein.	CRISPR-associated protein Cas4/endonuclease Cas1 fusion; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.627
KZX11909.1	cas2	MBFIL_13000	MBFIL_18010	Sugar-specific transcriptional regulator TrmB.	CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.516
KZX11909.1	cas4-cas1	MBFIL_13000	MBFIL_18020	Sugar-specific transcriptional regulator TrmB.	CRISPR-associated protein Cas4/endonuclease Cas1 fusion; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.518
KZX15378.1	cas2	MBFIL_06790	MBFIL_18010	PD-(D/E)XK nuclease superfamily protein.	CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.761
KZX15378.1	cas4-cas1	MBFIL_06790	MBFIL_18020	PD-(D/E)XK nuclease superfamily protein.	CRISPR-associated protein Cas4/endonuclease Cas1 fusion; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.627
KZX15390.1	KZX17621.1	MBFIL_06910	MBFIL_00310	Hypothetical protein.	Hypothetical protein.	0.505
KZX15390.1	cas2	MBFIL_06910	MBFIL_18010	Hypothetical protein.	CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.469
KZX15390.1	vapC_1	MBFIL_06910	MBFIL_00300	Hypothetical protein.	tRNA(fMet)-specific endonuclease VapC.	0.408
KZX15869.1	KZX11452.1	MBFIL_05810	MBFIL_14550	PD-(D/E)XK nuclease superfamily protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.	Hypothetical protein.	0.428
KZX15869.1	cas2	MBFIL_05810	MBFIL_18010	PD-(D/E)XK nuclease superfamily protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.	CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.809
KZX15869.1	cas4-cas1	MBFIL_05810	MBFIL_18020	PD-(D/E)XK nuclease superfamily protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.	CRISPR-associated protein Cas4/endonuclease Cas1 fusion; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.790
KZX15869.1	vapC_1	MBFIL_05810	MBFIL_00300	PD-(D/E)XK nuclease superfamily protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.	tRNA(fMet)-specific endonuclease VapC.	0.407
KZX17621.1	KZX11452.1	MBFIL_00310	MBFIL_14550	Hypothetical protein.	Hypothetical protein.	0.450
KZX17621.1	KZX15390.1	MBFIL_00310	MBFIL_06910	Hypothetical protein.	Hypothetical protein.	0.505
KZX17621.1	cas2	MBFIL_00310	MBFIL_18010	Hypothetical protein.	CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.	0.862

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