Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
purEN5-carboxyaminoimidazole ribonucleotide mutase. (428 aa)    
Predicted Functional Partners:
queC_1
7-cyano-7-deazaguanine synthase.
 
  
 0.968
KZX09883.1
Hypothetical protein; Belongs to the LarC family.
 
  
 0.965
mshD
Mycothiol acetyltransferase.
       0.720
nikMN
Fused nickel transport protein NikMN.
 
    0.585
cbiM_1
Cobalt transport protein CbiM precursor.
 
    0.557
KZX10242.1
Hypothetical protein.
       0.505
cbiM_2
Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.479
KZX10074.1
Cobalt transport protein CbiN.
  
    0.479
tsaD
tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family.
       0.466
moaB
Molybdenum cofactor biosynthesis protein B.
       0.465
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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