KZX10001.1 protein (Methanobrevibacter filiformis)

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KZX10001.1

Tetratricopeptide repeat protein. (335 aa)

Predicted Functional Partners:

dnaJ

0.847

dnaK

0.827

rpoH

0.813

alaS

0.808

ndk

0.787

rpoA

0.783

KZX11689.1

0.762

tagF_2

0.749

ftsH_2

0.738

KZX15130.1

0.736

Your Current Organism:

Methanobrevibacter filiformis

NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KZX10001.1	KZX11689.1	MBFIL_19350	MBFIL_13340	Tetratricopeptide repeat protein.	GMC oxidoreductase.	0.762
KZX10001.1	KZX15130.1	MBFIL_19350	MBFIL_07310	Tetratricopeptide repeat protein.	2',5' RNA ligase family; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.	0.736
KZX10001.1	alaS	MBFIL_19350	MBFIL_00150	Tetratricopeptide repeat protein.	alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.	0.808
KZX10001.1	dnaJ	MBFIL_19350	MBFIL_18660	Tetratricopeptide repeat protein.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.847
KZX10001.1	dnaK	MBFIL_19350	MBFIL_18650	Tetratricopeptide repeat protein.	Chaperone protein DnaK; Acts as a chaperone.	0.827
KZX10001.1	ftsH_2	MBFIL_19350	MBFIL_12420	Tetratricopeptide repeat protein.	ATP-dependent zinc metalloprotease FtsH.	0.738
KZX10001.1	ndk	MBFIL_19350	MBFIL_16780	Tetratricopeptide repeat protein.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	0.787
KZX10001.1	rpoA	MBFIL_19350	MBFIL_14050	Tetratricopeptide repeat protein.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.783
KZX10001.1	rpoH	MBFIL_19350	MBFIL_04910	Tetratricopeptide repeat protein.	DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.	0.813
KZX10001.1	tagF_2	MBFIL_19350	MBFIL_02620	Tetratricopeptide repeat protein.	CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase.	0.749
KZX11689.1	KZX10001.1	MBFIL_13340	MBFIL_19350	GMC oxidoreductase.	Tetratricopeptide repeat protein.	0.762
KZX11689.1	dnaK	MBFIL_13340	MBFIL_18650	GMC oxidoreductase.	Chaperone protein DnaK; Acts as a chaperone.	0.622
KZX15130.1	KZX10001.1	MBFIL_07310	MBFIL_19350	2',5' RNA ligase family; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.	Tetratricopeptide repeat protein.	0.736
alaS	KZX10001.1	MBFIL_00150	MBFIL_19350	alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.	Tetratricopeptide repeat protein.	0.808
alaS	dnaK	MBFIL_00150	MBFIL_18650	alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.	Chaperone protein DnaK; Acts as a chaperone.	0.498
alaS	rpoA	MBFIL_00150	MBFIL_14050	alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.464
dnaJ	KZX10001.1	MBFIL_18660	MBFIL_19350	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	Tetratricopeptide repeat protein.	0.847
dnaJ	dnaK	MBFIL_18660	MBFIL_18650	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	Chaperone protein DnaK; Acts as a chaperone.	0.999
dnaJ	ftsH_2	MBFIL_18660	MBFIL_12420	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	ATP-dependent zinc metalloprotease FtsH.	0.855
dnaJ	ndk	MBFIL_18660	MBFIL_16780	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.	0.826