STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fumBFumarate hydratase class I, anaerobic. (167 aa)    
Predicted Functional Partners:
ttdA
L(+)-tartrate dehydratase subunit alpha.
 
 0.994
KZX10113.1
Fumarate hydratase.
 
 0.994
frdA
Fumarate reductase flavoprotein subunit.
  
 
 0.967
ttdB
L(+)-tartrate dehydratase subunit beta.
  
  
 
0.946
frdB
Fumarate reductase iron-sulfur subunit.
    
 0.942
argH1
Argininosuccinate lyase 1.
    
 0.940
patA
Putative N-acetyl-LL-diaminopimelate aminotransferase.
    
 0.937
aspC
Aspartate aminotransferase.
     
  0.936
glpC
Anaerobic glycerol-3-phosphate dehydrogenase subunit C.
    
 0.843
hdc
Histidine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
       0.684
Your Current Organism:
Methanobrevibacter filiformis
NCBI taxonomy Id: 55758
Other names: DSM 11501, M. filiformis, strain RFM-3
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