STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarate hydratase, class II precursor; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (460 aa)    
Predicted Functional Partners:
sdhA
SdhA; Succinate dehydrogenase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.985
LHK_02342
Succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 0.974
frdA
FrdA; Succinate dehydrogenase or fumarate reductase, flavoprotein subunit.
 
 0.973
mdh
Mdh; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.972
maeB
MaeB; NADP-dependent malate dehydrogenase.
  
 
 0.971
fumB
FumB; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.970
sdhC
SdhC; Succinate dehydrogenase cytochrome b-556 subunit.
   
 
 0.961
LHK_02340
Fumarate reductase respiratory complex, transmembrane subunit.
   
 
 0.947
aceB
AceB; Malate synthase A; Belongs to the malate synthase family.
    
 0.938
sdhD
SdhD; Succinate dehydrogenase, hydrophobic subunit.
   
 
 0.917
Your Current Organism:
Laribacter hongkongensis
NCBI taxonomy Id: 557598
Other names: L. hongkongensis HLHK9, Laribacter hongkongensis HLHK9, Laribacter hongkongensis str. HLHK9, Laribacter hongkongensis strain HLHK9
Server load: low (18%) [HD]