node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LHK_01389 | LHK_01479 | LHK_01389 | LHK_01479 | DNA-directed DNA polymerase III, alpha subunit. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.825 |
LHK_01389 | LHK_01496 | LHK_01389 | LHK_01496 | DNA-directed DNA polymerase III, alpha subunit. | Single-stranded DNA-binding protein. | 0.825 |
LHK_01389 | dnaX | LHK_01389 | LHK_00963 | DNA-directed DNA polymerase III, alpha subunit. | DnaX; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.996 |
LHK_01389 | holC | LHK_01389 | LHK_01415 | DNA-directed DNA polymerase III, alpha subunit. | HolC; DNA polymerase III, chi subunit. | 0.994 |
LHK_01389 | topA | LHK_01389 | LHK_03143 | DNA-directed DNA polymerase III, alpha subunit. | TopA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally [...] | 0.610 |
LHK_01479 | LHK_01389 | LHK_01479 | LHK_01389 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA-directed DNA polymerase III, alpha subunit. | 0.825 |
LHK_01479 | LHK_01496 | LHK_01479 | LHK_01496 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Single-stranded DNA-binding protein. | 0.901 |
LHK_01479 | dnaX | LHK_01479 | LHK_00963 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DnaX; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.791 |
LHK_01479 | holC | LHK_01479 | LHK_01415 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | HolC; DNA polymerase III, chi subunit. | 0.765 |
LHK_01479 | priA | LHK_01479 | LHK_02821 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.798 |
LHK_01479 | rplV | LHK_01479 | LHK_00258 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | RplV; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.714 |
LHK_01479 | rpsB | LHK_01479 | LHK_02074 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | RpsB; 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.725 |
LHK_01479 | rpsF | LHK_01479 | LHK_02702 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | RpsF; Binds together with S18 to 16S ribosomal RNA. | 0.799 |
LHK_01479 | rpsJ | LHK_01479 | LHK_00252 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | rpsJ, nusE; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.746 |
LHK_01479 | topA | LHK_01479 | LHK_03143 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | TopA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally [...] | 0.983 |
LHK_01496 | LHK_01389 | LHK_01496 | LHK_01389 | Single-stranded DNA-binding protein. | DNA-directed DNA polymerase III, alpha subunit. | 0.825 |
LHK_01496 | LHK_01479 | LHK_01496 | LHK_01479 | Single-stranded DNA-binding protein. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.901 |
LHK_01496 | dnaX | LHK_01496 | LHK_00963 | Single-stranded DNA-binding protein. | DnaX; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.791 |
LHK_01496 | holC | LHK_01496 | LHK_01415 | Single-stranded DNA-binding protein. | HolC; DNA polymerase III, chi subunit. | 0.765 |
LHK_01496 | priA | LHK_01496 | LHK_02821 | Single-stranded DNA-binding protein. | PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.806 |