LHK_01655 protein (Laribacter hongkongensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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[Homology]

Score

LHK_01655

Hypothetical protein. (43 aa)

Predicted Functional Partners:

LHK_01656

0.671

LHK_01651

0.533

LHK_01652

0.533

LHK_01653

0.533

LHK_01654

0.533

LHK_01643

0.523

LHK_01645

0.523

LHK_01646

0.523

LHK_01647

0.523

LHK_01648

0.523

Your Current Organism:

Laribacter hongkongensis

NCBI taxonomy Id: 557598
Other names: L. hongkongensis HLHK9, Laribacter hongkongensis HLHK9, Laribacter hongkongensis str. HLHK9, Laribacter hongkongensis strain HLHK9

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
LHK_01643	LHK_01645	Hypothetical protein.	Probable bacteriophage tail core protein; Gp14, phage major tail tube protein.	0.773
LHK_01643	LHK_01646	Hypothetical protein.	Probable bacteriophage tail sheath protein.	0.773
LHK_01643	LHK_01647	Hypothetical protein.	Hypothetical protein.	0.773
LHK_01643	LHK_01648	Hypothetical protein.	Gp37 domain containing protein.	0.773
LHK_01643	LHK_01651	Hypothetical protein.	Putative capsid protein of prophage.	0.757
LHK_01643	LHK_01652	Hypothetical protein.	Hypothetical protein.	0.757
LHK_01643	LHK_01653	Hypothetical protein.	Periplasmic serine proteases (ClpP class).	0.756
LHK_01643	LHK_01654	Hypothetical protein.	Hypothetical protein.	0.756
LHK_01643	LHK_01655	Hypothetical protein.	Hypothetical protein.	0.523
LHK_01643	LHK_01656	Hypothetical protein.	CBS domain containing protein.	0.461
LHK_01645	LHK_01643	Probable bacteriophage tail core protein; Gp14, phage major tail tube protein.	Hypothetical protein.	0.773
LHK_01645	LHK_01646	Probable bacteriophage tail core protein; Gp14, phage major tail tube protein.	Probable bacteriophage tail sheath protein.	0.984
LHK_01645	LHK_01647	Probable bacteriophage tail core protein; Gp14, phage major tail tube protein.	Hypothetical protein.	0.773
LHK_01645	LHK_01648	Probable bacteriophage tail core protein; Gp14, phage major tail tube protein.	Gp37 domain containing protein.	0.773
LHK_01645	LHK_01651	Probable bacteriophage tail core protein; Gp14, phage major tail tube protein.	Putative capsid protein of prophage.	0.903
LHK_01645	LHK_01652	Probable bacteriophage tail core protein; Gp14, phage major tail tube protein.	Hypothetical protein.	0.910
LHK_01645	LHK_01653	Probable bacteriophage tail core protein; Gp14, phage major tail tube protein.	Periplasmic serine proteases (ClpP class).	0.809
LHK_01645	LHK_01654	Probable bacteriophage tail core protein; Gp14, phage major tail tube protein.	Hypothetical protein.	0.756
LHK_01645	LHK_01655	Probable bacteriophage tail core protein; Gp14, phage major tail tube protein.	Hypothetical protein.	0.523
LHK_01645	LHK_01656	Probable bacteriophage tail core protein; Gp14, phage major tail tube protein.	CBS domain containing protein.	0.461

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

24

average node degree:

4.36

avg. local clustering coefficient:

0.856

expected number of edges:

33

PPI enrichment p-value:

0.959

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2713

Alpha/beta hydrolase fold-1

4 of 6

2.57

3.35

1.13e-06

CL:1085

Phosphopantetheine attachment site, and Thioesterase domain

2 of 10

2.04

0.79

0.0417

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031975

Envelope

4 of 85

1.42

1.1

0.0033

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0596

Phosphopantetheine

3 of 47

1.55

0.9

0.0158

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00561

Alpha/beta hydrolase fold

3 of 22

1.88

1.19

0.0061

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000073

Alpha/beta hydrolase fold-1

4 of 22

2.0

2.04

0.00012

IPR032821

Polyketide synthase, C-terminal extension

3 of 16

2.02

1.4

0.0028

IPR013968

Polyketide synthase, ketoreductase domain

3 of 15

2.04

1.4

0.0028

IPR016036

Malonyl-CoA ACP transacylase, ACP-binding

3 of 17

1.99

1.39

0.0028

IPR014043

Acyl transferase

3 of 17

1.99

1.39

0.0028

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00822

This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.

3 of 13

2.11

1.88

0.00034

SM00827

Acyl transferase domain in polyketide synthase (PKS) enzymes.

3 of 15

2.04

1.85

0.00034

SM00823

Phosphopantetheine attachment site

3 of 16

2.02

1.84

0.00034

SM00826

PKS_DH

2 of 4

2.44

1.61

0.0016

SM00825

Beta-ketoacyl synthase

2 of 12

1.96

1.16

0.0078

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