node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LHK_00487 | LHK_00590 | LHK_00487 | LHK_00590 | Universal stress protein UspA and related nucleotide-binding protein. | Universal stress protein UspA and related nucleotide-binding protein. | 0.681 |
LHK_00487 | LHK_01454 | LHK_00487 | LHK_01454 | Universal stress protein UspA and related nucleotide-binding protein. | Universal stress protein. | 0.681 |
LHK_00487 | LHK_01835 | LHK_00487 | LHK_01835 | Universal stress protein UspA and related nucleotide-binding protein. | Putative stress response DNA-binding protein; Belongs to the Dps family. | 0.728 |
LHK_00487 | LHK_03102 | LHK_00487 | LHK_03102 | Universal stress protein UspA and related nucleotide-binding protein. | Universal stress protein family. | 0.681 |
LHK_00487 | dnaJ | LHK_00487 | LHK_02738 | Universal stress protein UspA and related nucleotide-binding protein. | DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are r [...] | 0.732 |
LHK_00487 | groEL1-1 | LHK_00487 | LHK_00660 | Universal stress protein UspA and related nucleotide-binding protein. | GroEL1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.722 |
LHK_00487 | grpE | LHK_00487 | LHK_02740 | Universal stress protein UspA and related nucleotide-binding protein. | GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interacti [...] | 0.703 |
LHK_00487 | hscA | LHK_00487 | LHK_02861 | Universal stress protein UspA and related nucleotide-binding protein. | HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.689 |
LHK_00487 | uspA | LHK_00487 | LHK_00889 | Universal stress protein UspA and related nucleotide-binding protein. | UspA; Universal stress protein UspA and related nucleotide-binding proteins. | 0.681 |
LHK_00590 | LHK_00487 | LHK_00590 | LHK_00487 | Universal stress protein UspA and related nucleotide-binding protein. | Universal stress protein UspA and related nucleotide-binding protein. | 0.681 |
LHK_00590 | LHK_01835 | LHK_00590 | LHK_01835 | Universal stress protein UspA and related nucleotide-binding protein. | Putative stress response DNA-binding protein; Belongs to the Dps family. | 0.728 |
LHK_00590 | LHK_03102 | LHK_00590 | LHK_03102 | Universal stress protein UspA and related nucleotide-binding protein. | Universal stress protein family. | 0.416 |
LHK_00590 | dnaJ | LHK_00590 | LHK_02738 | Universal stress protein UspA and related nucleotide-binding protein. | DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are r [...] | 0.732 |
LHK_00590 | groEL1-1 | LHK_00590 | LHK_00660 | Universal stress protein UspA and related nucleotide-binding protein. | GroEL1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.722 |
LHK_00590 | grpE | LHK_00590 | LHK_02740 | Universal stress protein UspA and related nucleotide-binding protein. | GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interacti [...] | 0.703 |
LHK_00590 | hscA | LHK_00590 | LHK_02861 | Universal stress protein UspA and related nucleotide-binding protein. | HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.689 |
LHK_00590 | uspA | LHK_00590 | LHK_00889 | Universal stress protein UspA and related nucleotide-binding protein. | UspA; Universal stress protein UspA and related nucleotide-binding proteins. | 0.430 |
LHK_01454 | LHK_00487 | LHK_01454 | LHK_00487 | Universal stress protein. | Universal stress protein UspA and related nucleotide-binding protein. | 0.681 |
LHK_01454 | LHK_01835 | LHK_01454 | LHK_01835 | Universal stress protein. | Putative stress response DNA-binding protein; Belongs to the Dps family. | 0.728 |
LHK_01454 | dnaJ | LHK_01454 | LHK_02738 | Universal stress protein. | DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are r [...] | 0.732 |