node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LHK_01397 | LHK_02892 | LHK_01397 | LHK_02892 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | Probable electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. | 0.741 |
LHK_01397 | folB | LHK_01397 | LHK_00622 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | FolB; Dihydroneopterin aldolase. | 0.996 |
LHK_01397 | folC | LHK_01397 | LHK_02114 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | FolC; Folylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | 0.947 |
LHK_01397 | folP | LHK_01397 | LHK_02899 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
LHK_02892 | LHK_01397 | LHK_02892 | LHK_01397 | Probable electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.741 |
LHK_02892 | folP | LHK_02892 | LHK_02899 | Probable electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. | FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.710 |
folB | LHK_01397 | LHK_00622 | LHK_01397 | FolB; Dihydroneopterin aldolase. | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.996 |
folB | folC | LHK_00622 | LHK_02114 | FolB; Dihydroneopterin aldolase. | FolC; Folylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | 0.744 |
folB | folP | LHK_00622 | LHK_02899 | FolB; Dihydroneopterin aldolase. | FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.996 |
folB | hflB | LHK_00622 | LHK_02901 | FolB; Dihydroneopterin aldolase. | HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.513 |
folB | pabC | LHK_00622 | LHK_02554 | FolB; Dihydroneopterin aldolase. | PabC; 4-amino-4-deoxychorismate lyase. | 0.402 |
folC | LHK_01397 | LHK_02114 | LHK_01397 | FolC; Folylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.947 |
folC | folB | LHK_02114 | LHK_00622 | FolC; Folylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | FolB; Dihydroneopterin aldolase. | 0.744 |
folC | folP | LHK_02114 | LHK_02899 | FolC; Folylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.997 |
folP | LHK_01397 | LHK_02899 | LHK_01397 | FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.999 |
folP | LHK_02892 | LHK_02899 | LHK_02892 | FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Probable electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. | 0.710 |
folP | folB | LHK_02899 | LHK_00622 | FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | FolB; Dihydroneopterin aldolase. | 0.996 |
folP | folC | LHK_02899 | LHK_02114 | FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | FolC; Folylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | 0.997 |
folP | glmM | LHK_02899 | LHK_02898 | FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GlmM; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.923 |
folP | gyrA | LHK_02899 | LHK_01836 | FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | GyrA; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.726 |