STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tolC4TolC4; Probable outer membrane multidrug resistance lipoprotein. (467 aa)    
Predicted Functional Partners:
LHK_03133
Efflux pump membrane protein.
 
 0.928
macB
ABC transporter, ATP-binding/permease protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.801
emrB
EmrB; Multidrug resistance protein B; Belongs to the major facilitator superfamily.
 
  
 0.801
LHK_02929
Probable multidrug efflux membrane permease; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   0.786
LHK_02129
Multidrug resistance protein; Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   0.783
LHK_01374
Secretion protein HlyD family protein.
 
 0.780
LHK_03135
Metal dependent phosphohydrolase.
       0.757
LHK_01426
Efflux transporter, RND family, MFP subunit; Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   0.745
LHK_02130
Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; Hydrophobe/amphiphile efflux-1 HAE1 precursor.
   0.708
LHK_01425
Cation/multidrug efflux pump.
   0.624
Your Current Organism:
Laribacter hongkongensis
NCBI taxonomy Id: 557598
Other names: L. hongkongensis HLHK9, Laribacter hongkongensis HLHK9, Laribacter hongkongensis str. HLHK9, Laribacter hongkongensis strain HLHK9
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