node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEP66524.1 | CEP66761.1 | 590 | 838 | L,D-transpeptidase catalytic domain. | Cell wall hydrolase/autolysin, catalytic. | 0.691 |
CEP66524.1 | CEP67095.1 | 590 | 1253 | L,D-transpeptidase catalytic domain. | Cell wall hydrolase/autolysin, catalytic. | 0.931 |
CEP66524.1 | CEP67647.1 | 590 | 1736 | L,D-transpeptidase catalytic domain. | Cell wall hydrolase/autolysin, catalytic. | 0.691 |
CEP66524.1 | CEP67812.1 | 590 | 1903 | L,D-transpeptidase catalytic domain. | Cell wall hydrolase, SleB. | 0.649 |
CEP66524.1 | CEP69057.1 | 590 | 3161 | L,D-transpeptidase catalytic domain. | Beta-lactamase/transpeptidase-like. | 0.835 |
CEP66524.1 | cinA | 590 | 2951 | L,D-transpeptidase catalytic domain. | Competence-induced protein CinA; Belongs to the CinA family. | 0.482 |
CEP66761.1 | CEP66524.1 | 838 | 590 | Cell wall hydrolase/autolysin, catalytic. | L,D-transpeptidase catalytic domain. | 0.691 |
CEP66761.1 | CEP67095.1 | 838 | 1253 | Cell wall hydrolase/autolysin, catalytic. | Cell wall hydrolase/autolysin, catalytic. | 0.821 |
CEP66761.1 | CEP67456.1 | 838 | 1545 | Cell wall hydrolase/autolysin, catalytic. | Domain of unknown function DUF4367. | 0.736 |
CEP66761.1 | CEP67647.1 | 838 | 1736 | Cell wall hydrolase/autolysin, catalytic. | Cell wall hydrolase/autolysin, catalytic. | 0.826 |
CEP66761.1 | cinA | 838 | 2951 | Cell wall hydrolase/autolysin, catalytic. | Competence-induced protein CinA; Belongs to the CinA family. | 0.448 |
CEP67091.1 | CEP67095.1 | 1249 | 1253 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Cell wall hydrolase/autolysin, catalytic. | 0.812 |
CEP67091.1 | CEP67812.1 | 1249 | 1903 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Cell wall hydrolase, SleB. | 0.474 |
CEP67091.1 | CEP69057.1 | 1249 | 3161 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Beta-lactamase/transpeptidase-like. | 0.501 |
CEP67091.1 | guaA | 1249 | 3216 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.974 |
CEP67091.1 | guaB | 1249 | 2772 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.939 |
CEP67095.1 | CEP66524.1 | 1253 | 590 | Cell wall hydrolase/autolysin, catalytic. | L,D-transpeptidase catalytic domain. | 0.931 |
CEP67095.1 | CEP66761.1 | 1253 | 838 | Cell wall hydrolase/autolysin, catalytic. | Cell wall hydrolase/autolysin, catalytic. | 0.821 |
CEP67095.1 | CEP67091.1 | 1253 | 1249 | Cell wall hydrolase/autolysin, catalytic. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.812 |
CEP67095.1 | CEP67456.1 | 1253 | 1545 | Cell wall hydrolase/autolysin, catalytic. | Domain of unknown function DUF4367. | 0.775 |