node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEP66325.1 | CEP67146.1 | 376 | 1304 | ATPase, AAA-type, core; Belongs to the ClpA/ClpB family. | Uncharacterized. | 0.976 |
CEP66325.1 | CEP67961.1 | 376 | 2164 | ATPase, AAA-type, core; Belongs to the ClpA/ClpB family. | Uncharacterized. | 0.976 |
CEP66325.1 | CEP68870.1 | 376 | 2976 | ATPase, AAA-type, core; Belongs to the ClpA/ClpB family. | Heat shock protein 70 family. | 0.984 |
CEP66325.1 | dnaJ | 376 | 2438 | ATPase, AAA-type, core; Belongs to the ClpA/ClpB family. | Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.948 |
CEP66325.1 | dnaK | 376 | 2439 | ATPase, AAA-type, core; Belongs to the ClpA/ClpB family. | Chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.984 |
CEP66325.1 | groL | 376 | 1208 | ATPase, AAA-type, core; Belongs to the ClpA/ClpB family. | Chaperonin Cpn60; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.931 |
CEP66325.1 | grpE | 376 | 2440 | ATPase, AAA-type, core; Belongs to the ClpA/ClpB family. | GrpE nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.941 |
CEP66325.1 | grpE-2 | 376 | 2975 | ATPase, AAA-type, core; Belongs to the ClpA/ClpB family. | GrpE nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.941 |
CEP66325.1 | hrcA | 376 | 2441 | ATPase, AAA-type, core; Belongs to the ClpA/ClpB family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.899 |
CEP66398.1 | CEP67146.1 | 456 | 1304 | NADH:ubiquinone oxidoreductase, 51kDa subunit. | Uncharacterized. | 0.484 |
CEP66398.1 | CEP67961.1 | 456 | 2164 | NADH:ubiquinone oxidoreductase, 51kDa subunit. | Uncharacterized. | 0.484 |
CEP66398.1 | CEP68870.1 | 456 | 2976 | NADH:ubiquinone oxidoreductase, 51kDa subunit. | Heat shock protein 70 family. | 0.484 |
CEP66398.1 | dnaJ | 456 | 2438 | NADH:ubiquinone oxidoreductase, 51kDa subunit. | Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.884 |
CEP66398.1 | dnaK | 456 | 2439 | NADH:ubiquinone oxidoreductase, 51kDa subunit. | Chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.484 |
CEP66398.1 | groL | 456 | 1208 | NADH:ubiquinone oxidoreductase, 51kDa subunit. | Chaperonin Cpn60; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.625 |
CEP67146.1 | CEP66325.1 | 1304 | 376 | Uncharacterized. | ATPase, AAA-type, core; Belongs to the ClpA/ClpB family. | 0.976 |
CEP67146.1 | CEP66398.1 | 1304 | 456 | Uncharacterized. | NADH:ubiquinone oxidoreductase, 51kDa subunit. | 0.484 |
CEP67146.1 | dnaJ | 1304 | 2438 | Uncharacterized. | Chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.955 |
CEP67146.1 | groL | 1304 | 1208 | Uncharacterized. | Chaperonin Cpn60; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.946 |
CEP67146.1 | grpE | 1304 | 2440 | Uncharacterized. | GrpE nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.962 |