node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEP66908.1 | ffh | 1064 | 2544 | Preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle, SRP54 subunit; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.981 |
CEP66908.1 | ftsY | 1064 | 2548 | Preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal-recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.983 |
CEP66908.1 | rplD | 1064 | 2247 | Preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Ribosomal protein L4/L1e, bacterial-type; Forms part of the polypeptide exit tunnel. | 0.823 |
CEP66908.1 | rplM | 1064 | 2213 | Preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.983 |
CEP66908.1 | rplS | 1064 | 2539 | Preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.963 |
CEP66908.1 | rpsP | 1064 | 2543 | Preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.653 |
CEP66908.1 | secE | 1064 | 3145 | Preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.999 |
CEP66908.1 | secY | 1064 | 2228 | Preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.995 |
CEP68342.1 | ffh | 2545 | 2544 | RNA polymerase sigma factor, region 3/4; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Signal recognition particle, SRP54 subunit; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.978 |
CEP68342.1 | ftsY | 2545 | 2548 | RNA polymerase sigma factor, region 3/4; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Signal-recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.636 |
CEP68342.1 | rplS | 2545 | 2539 | RNA polymerase sigma factor, region 3/4; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.513 |
CEP68342.1 | rpsP | 2545 | 2543 | RNA polymerase sigma factor, region 3/4; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.680 |
ffh | CEP66908.1 | 2544 | 1064 | Signal recognition particle, SRP54 subunit; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.981 |
ffh | CEP68342.1 | 2544 | 2545 | Signal recognition particle, SRP54 subunit; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | RNA polymerase sigma factor, region 3/4; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | 0.978 |
ffh | ftsY | 2544 | 2548 | Signal recognition particle, SRP54 subunit; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Signal-recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.997 |
ffh | rplD | 2544 | 2247 | Signal recognition particle, SRP54 subunit; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Ribosomal protein L4/L1e, bacterial-type; Forms part of the polypeptide exit tunnel. | 0.970 |
ffh | rplM | 2544 | 2213 | Signal recognition particle, SRP54 subunit; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.966 |
ffh | rplS | 2544 | 2539 | Signal recognition particle, SRP54 subunit; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.978 |
ffh | rpsE | 2544 | 2231 | Signal recognition particle, SRP54 subunit; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Ribosomal protein S5, bacterial-type; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.971 |
ffh | rpsP | 2544 | 2543 | Signal recognition particle, SRP54 subunit; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.991 |