STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobSCobalamin (vitamin B12) biosynthesis CobS,cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (255 aa)    
Predicted Functional Partners:
CEP68687.1
Tetrapyrrole methylase.
 
  
 0.998
cobT
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
 
 0.993
CEP68695.1
Cobinamide kinase/cobinamide phosphate guanyltransferase.
 
 
 0.991
CEP68675.1
Alpha-ribazole phosphatase, CobC; Belongs to the phosphoglycerate mutase family.
 
 
 0.988
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.988
CEP67638.1
Nucleic acid-binding, OB-fold.
   
    0.978
CEP69620.1
Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR.
 
 
 0.978
cobD
Cobalamin biosynthesis CobD/CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.969
CEP68689.1
Tetrapyrrole methylase.
 
 
 0.952
CEP68680.1
Cobyrinic acid a,c-diamide synthase CbiA.
 
  
 0.944
Your Current Organism:
Moorella glycerini
NCBI taxonomy Id: 55779
Other names: ATCC 700316, DSM 11254, M. glycerini, strain JW/AS-Y6
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