node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KMQ60094.1 | KMQ64752.1 | ACM46_17785 | ACM46_10985 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | 0.722 |
KMQ60094.1 | gcvT | ACM46_17785 | ACM46_14550 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.525 |
KMQ60094.1 | glyA | ACM46_17785 | ACM46_06790 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.966 |
KMQ64698.1 | KMQ64752.1 | ACM46_10660 | ACM46_10985 | Phosphoribosylformylglycinamidine synthase; Catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | 0.987 |
KMQ64698.1 | folD | ACM46_10660 | ACM46_04700 | Phosphoribosylformylglycinamidine synthase; Catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.843 |
KMQ64698.1 | gcvH | ACM46_10660 | ACM46_00010 | Phosphoribosylformylglycinamidine synthase; Catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.599 |
KMQ64698.1 | gcvT | ACM46_10660 | ACM46_14550 | Phosphoribosylformylglycinamidine synthase; Catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.598 |
KMQ64698.1 | glyA | ACM46_10660 | ACM46_06790 | Phosphoribosylformylglycinamidine synthase; Catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.978 |
KMQ64698.1 | purH | ACM46_10660 | ACM46_14325 | Phosphoribosylformylglycinamidine synthase; Catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
KMQ64698.1 | purN | ACM46_10660 | ACM46_14330 | Phosphoribosylformylglycinamidine synthase; Catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
KMQ64752.1 | KMQ60094.1 | ACM46_10985 | ACM46_17785 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.722 |
KMQ64752.1 | KMQ64698.1 | ACM46_10985 | ACM46_10660 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Phosphoribosylformylglycinamidine synthase; Catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.987 |
KMQ64752.1 | KMQ66104.1 | ACM46_10985 | ACM46_00630 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | 5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. | 0.764 |
KMQ64752.1 | KMQ66616.1 | ACM46_10985 | ACM46_03595 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.737 |
KMQ64752.1 | folD | ACM46_10985 | ACM46_04700 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | 5,10-methylene-tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.893 |
KMQ64752.1 | gcvH | ACM46_10985 | ACM46_00010 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
KMQ64752.1 | gcvT | ACM46_10985 | ACM46_14550 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
KMQ64752.1 | glyA | ACM46_10985 | ACM46_06790 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.998 |
KMQ64752.1 | purH | ACM46_10985 | ACM46_14325 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.784 |
KMQ66104.1 | KMQ64752.1 | ACM46_00630 | ACM46_10985 | 5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | 0.764 |