| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GcvP | IQ37_04735 | IQ37_09040 | IQ37_04735 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.474 |
| GcvP | IQ37_07180 | IQ37_09040 | IQ37_07180 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.604 |
| GcvP | gcvH | IQ37_09040 | IQ37_19640 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| GcvP | gcvT | IQ37_09040 | IQ37_12975 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| GcvP | thyA | IQ37_09040 | IQ37_14295 | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.699 |
| IQ37_04735 | GcvP | IQ37_04735 | IQ37_09040 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | 0.474 |
| IQ37_04735 | IQ37_07180 | IQ37_04735 | IQ37_07180 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.418 |
| IQ37_04735 | IQ37_07185 | IQ37_04735 | IQ37_07185 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. | Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.657 |
| IQ37_04735 | gcvH | IQ37_04735 | IQ37_19640 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.640 |
| IQ37_04735 | gcvT | IQ37_04735 | IQ37_12975 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.406 |
| IQ37_07180 | GcvP | IQ37_07180 | IQ37_09040 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvP family. | 0.604 |
| IQ37_07180 | IQ37_04735 | IQ37_07180 | IQ37_04735 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.418 |
| IQ37_07180 | IQ37_07185 | IQ37_07180 | IQ37_07185 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.749 |
| IQ37_07180 | IQ37_10390 | IQ37_07180 | IQ37_10390 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. | 0.552 |
| IQ37_07180 | IQ37_15505 | IQ37_07180 | IQ37_15505 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.444 |
| IQ37_07180 | gcvH | IQ37_07180 | IQ37_19640 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.549 |
| IQ37_07180 | gcvT | IQ37_07180 | IQ37_12975 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.554 |
| IQ37_07180 | thyA | IQ37_07180 | IQ37_14295 | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.830 |
| IQ37_07185 | IQ37_04735 | IQ37_07185 | IQ37_04735 | Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.657 |
| IQ37_07185 | IQ37_07180 | IQ37_07185 | IQ37_07180 | Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.749 |