STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQ37_08875Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (739 aa)    
Predicted Functional Partners:
IQ37_16800
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
  
 0.943
IQ37_09380
Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.937
IQ37_09375
Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.918
acnA
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.918
IQ37_03545
2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.916
IQ37_13960
Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
  0.828
IQ37_01285
Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.819
argH
Argininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.810
gltD
Glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.809
IQ37_01890
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.804
Your Current Organism:
Chryseobacterium piperi
NCBI taxonomy Id: 558152
Other names: C. piperi, CCUG 57707, Chryseobacterium piperi Strahan et al. 2011 emend. Hahnke et al. 2016, Chryseobacterium sp. CTM, DSM 22249, JCM 15960, KCTC 23267, strain CTM
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.