Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AIT59896.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (80 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.831
AIT60914.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.668
AIT60361.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.610
AIT61190.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.564
AIT61098.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.558
AIT60336.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.557
AIT59893.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.556
AIT59894.1
CopG family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.556
secE
Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
  
     0.552
AIT61297.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.527
Your Current Organism:
Corynebacterium doosanense
NCBI taxonomy Id: 558173
Other names: C. doosanense CAU 212 = DSM 45436, Corynebacterium doosanense CAU 212, Corynebacterium doosanense CAU 212 = DSM 45436, Corynebacterium doosanense DSM 45436, Corynebacterium doosanense DSM 45436 = CAU 212, Corynebacterium sp. CAU 212
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