STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIT59934.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)    
Predicted Functional Partners:
AIT59995.1
Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.927
AIT61943.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
 
 
 0.926
AIT61898.1
Phosphotransacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.747
AIT60182.1
Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
0.668
AIT62082.1
2,4-dienoyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.512
AIT60212.1
ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.460
leuC
Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
    
 
 0.459
AIT60736.1
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.452
ilvD
Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family.
   
 
 0.433
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
      
 0.422
Your Current Organism:
Corynebacterium doosanense
NCBI taxonomy Id: 558173
Other names: C. doosanense CAU 212 = DSM 45436, Corynebacterium doosanense CAU 212, Corynebacterium doosanense CAU 212 = DSM 45436, Corynebacterium doosanense DSM 45436, Corynebacterium doosanense DSM 45436 = CAU 212, Corynebacterium sp. CAU 212
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