Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
menCO-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (338 aa)    
Predicted Functional Partners:
AIT60247.1
O-succinylbenzoic acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.961
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
   
 0.949
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
 
   
 0.895
AIT60260.1
Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.834
menG
Ubiquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
     
 0.803
AIT60263.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.800
AIT60261.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.775
AIT60258.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S51 family.
       0.729
AIT60721.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.666
AIT60264.1
GDP-mannose-dependent alpha-mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.617
Your Current Organism:
Corynebacterium doosanense
NCBI taxonomy Id: 558173
Other names: C. doosanense CAU 212 = DSM 45436, Corynebacterium doosanense CAU 212, Corynebacterium doosanense CAU 212 = DSM 45436, Corynebacterium doosanense DSM 45436, Corynebacterium doosanense DSM 45436 = CAU 212, Corynebacterium sp. CAU 212
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