| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AIT59886.1 | AIT60149.1 | CDOO_00015 | CDOO_01775 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
| AIT59886.1 | AIT60577.1 | CDOO_00015 | CDOO_04430 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.797 |
| AIT59886.1 | gyrB | CDOO_00015 | CDOO_00030 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.887 |
| AIT59886.1 | polA | CDOO_00015 | CDOO_06735 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.992 |
| AIT59886.1 | recA | CDOO_00015 | CDOO_08565 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.899 |
| AIT59886.1 | topA | CDOO_00015 | CDOO_01740 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.714 |
| AIT60149.1 | AIT59886.1 | CDOO_01775 | CDOO_00015 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.993 |
| AIT60149.1 | AIT60577.1 | CDOO_01775 | CDOO_04430 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.787 |
| AIT60149.1 | AIT60739.1 | CDOO_01775 | CDOO_05335 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.610 |
| AIT60149.1 | AIT60815.1 | CDOO_01775 | CDOO_05785 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.610 |
| AIT60149.1 | AIT60816.1 | CDOO_01775 | CDOO_05790 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.490 |
| AIT60149.1 | gyrB | CDOO_01775 | CDOO_00030 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.524 |
| AIT60149.1 | polA | CDOO_01775 | CDOO_06735 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.888 |
| AIT60149.1 | recA | CDOO_01775 | CDOO_08565 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.630 |
| AIT60149.1 | topA | CDOO_01775 | CDOO_01740 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.648 |
| AIT60577.1 | AIT59886.1 | CDOO_04430 | CDOO_00015 | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.797 |
| AIT60577.1 | AIT60149.1 | CDOO_04430 | CDOO_01775 | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.787 |
| AIT60577.1 | AIT60739.1 | CDOO_04430 | CDOO_05335 | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.786 |
| AIT60577.1 | AIT60815.1 | CDOO_04430 | CDOO_05785 | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.786 |
| AIT60577.1 | AIT60816.1 | CDOO_04430 | CDOO_05790 | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.846 |