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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIT61646.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)    
Predicted Functional Partners:
AIT61645.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.972
AIT61802.1
Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.917
AIT60447.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.914
AIT60217.1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.911
AIT60556.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.911
AIT60175.1
PhoR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.904
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.776
AIT61502.1
Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.711
AIT59901.1
Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.654
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.636
Your Current Organism:
Corynebacterium doosanense
NCBI taxonomy Id: 558173
Other names: C. doosanense CAU 212 = DSM 45436, Corynebacterium doosanense CAU 212, Corynebacterium doosanense CAU 212 = DSM 45436, Corynebacterium doosanense DSM 45436, Corynebacterium doosanense DSM 45436 = CAU 212, Corynebacterium sp. CAU 212
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