| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AIT60563.1 | AIT61728.1 | CDOO_04350 | CDOO_10955 | 5-formyltetrahydrofolate cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.475 |
| AIT61724.1 | AIT61726.1 | CDOO_10935 | CDOO_10945 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.786 |
| AIT61724.1 | AIT61728.1 | CDOO_10935 | CDOO_10955 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.635 |
| AIT61724.1 | AIT61729.1 | CDOO_10935 | CDOO_10960 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.597 |
| AIT61724.1 | AIT61731.1 | CDOO_10935 | CDOO_10970 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.526 |
| AIT61724.1 | clpS | CDOO_10935 | CDOO_10965 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Clp protease ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.581 |
| AIT61724.1 | murI | CDOO_10935 | CDOO_10950 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.964 |
| AIT61724.1 | rph | CDOO_10935 | CDOO_10940 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.990 |
| AIT61726.1 | AIT61724.1 | CDOO_10945 | CDOO_10935 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.786 |
| AIT61726.1 | AIT61728.1 | CDOO_10945 | CDOO_10955 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.667 |
| AIT61726.1 | AIT61729.1 | CDOO_10945 | CDOO_10960 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.625 |
| AIT61726.1 | AIT61731.1 | CDOO_10945 | CDOO_10970 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.583 |
| AIT61726.1 | clpS | CDOO_10945 | CDOO_10965 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Clp protease ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.607 |
| AIT61726.1 | murI | CDOO_10945 | CDOO_10950 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.701 |
| AIT61726.1 | rph | CDOO_10945 | CDOO_10940 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.829 |
| AIT61728.1 | AIT60563.1 | CDOO_10955 | CDOO_04350 | Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-formyltetrahydrofolate cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.475 |
| AIT61728.1 | AIT61724.1 | CDOO_10955 | CDOO_10935 | Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.635 |
| AIT61728.1 | AIT61726.1 | CDOO_10955 | CDOO_10945 | Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.667 |
| AIT61728.1 | AIT61729.1 | CDOO_10955 | CDOO_10960 | Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.816 |
| AIT61728.1 | AIT61731.1 | CDOO_10955 | CDOO_10970 | Rhomboid family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.602 |