BDCG_17336 protein (Blastomyces dermatitidis)

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Score

BDCG_17336

2-oxoglutarate dehydrogenase E2 component (Dihydrolipoamide succinyltransferase). (231 aa)

Predicted Functional Partners:

BDCG_08905

0.997

BDCG_06535

0.993

BDCG_03491

0.955

BDCG_09385

0.948

BDCG_02519

0.946

BDCG_17335

0.944

BDCG_01953

0.942

BDCG_02254

0.930

BDCG_08715

0.930

BDCG_08451

0.919

Your Current Organism:

Blastomyces dermatitidis

NCBI taxonomy Id: 559297
Other names: Ajellomyces dermatitidis ER-3, B. dermatitidis ER-3, Blastomyces dermatitidis ER-3

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDCG_01953	BDCG_02254	C5GC70	C5GAY0	2-oxoisovalerate dehydrogenase E1 component, beta subunit.	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.632
BDCG_01953	BDCG_02519	C5GC70	C5GDR2	2-oxoisovalerate dehydrogenase E1 component, beta subunit.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.956
BDCG_01953	BDCG_03491	C5GC70	C5GGX6	2-oxoisovalerate dehydrogenase E1 component, beta subunit.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.999
BDCG_01953	BDCG_06535	C5GC70	C5GRA5	2-oxoisovalerate dehydrogenase E1 component, beta subunit.	Dihydrolipoyl dehydrogenase.	0.992
BDCG_01953	BDCG_08451	C5GC70	C5GVU0	2-oxoisovalerate dehydrogenase E1 component, beta subunit.	Succinyl-CoA synthetase alpha subunit.	0.632
BDCG_01953	BDCG_08715	C5GC70	C5GWW3	2-oxoisovalerate dehydrogenase E1 component, beta subunit.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.535
BDCG_01953	BDCG_08905	C5GC70	C5GWY1	2-oxoisovalerate dehydrogenase E1 component, beta subunit.	Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component.	0.858
BDCG_01953	BDCG_09385	C5GC70	C5GYE7	2-oxoisovalerate dehydrogenase E1 component, beta subunit.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.687
BDCG_01953	BDCG_17335	C5GC70	A0A179U670	2-oxoisovalerate dehydrogenase E1 component, beta subunit.	2-oxoglutarate dehydrogenase E2 component (Dihydrolipoamide succinyltransferase).	0.952
BDCG_01953	BDCG_17336	C5GC70	A0A179U2P9	2-oxoisovalerate dehydrogenase E1 component, beta subunit.	2-oxoglutarate dehydrogenase E2 component (Dihydrolipoamide succinyltransferase).	0.942
BDCG_02254	BDCG_01953	C5GAY0	C5GC70	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	2-oxoisovalerate dehydrogenase E1 component, beta subunit.	0.632
BDCG_02254	BDCG_02519	C5GAY0	C5GDR2	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.913
BDCG_02254	BDCG_03491	C5GAY0	C5GGX6	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.534
BDCG_02254	BDCG_06535	C5GAY0	C5GRA5	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Dihydrolipoyl dehydrogenase.	0.855
BDCG_02254	BDCG_08451	C5GAY0	C5GVU0	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Succinyl-CoA synthetase alpha subunit.	0.880
BDCG_02254	BDCG_08715	C5GAY0	C5GWW3	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.999
BDCG_02254	BDCG_08905	C5GAY0	C5GWY1	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component.	0.984
BDCG_02254	BDCG_09385	C5GAY0	C5GYE7	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.803
BDCG_02254	BDCG_17335	C5GAY0	A0A179U670	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	2-oxoglutarate dehydrogenase E2 component (Dihydrolipoamide succinyltransferase).	0.932
BDCG_02254	BDCG_17336	C5GAY0	A0A179U2P9	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	2-oxoglutarate dehydrogenase E2 component (Dihydrolipoamide succinyltransferase).	0.930