STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BDCG_08200E3 ubiquitin-protein ligase HUWE1. (4142 aa)    
Predicted Functional Partners:
BDCG_03270
Polyubiquitin.
   
 0.952
BDCG_00342
BZIP domain-containing protein.
   
 0.806
BDCG_01171
Ubiquitin-40S ribosomal protein S27a, variant.
   
 0.806
BDCG_06846
Zinc finger protein.
    
 0.799
BDCG_07508
Uncharacterized protein.
    
 0.799
BDCG_07509
50S ribosomal protein L40e.
    
 0.799
BDCG_03507
E3 ubiquitin-protein ligase TRIP12.
   
 
0.782
BDCG_01363
Uncharacterized protein.
   
 0.753
BDCG_04507
Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.
   
 
 0.724
BDCG_07653
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 
 0.699
Your Current Organism:
Blastomyces dermatitidis
NCBI taxonomy Id: 559297
Other names: Ajellomyces dermatitidis ER-3, B. dermatitidis ER-3, Blastomyces dermatitidis ER-3
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