STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BDCG_00143Uncharacterized protein. (183 aa)    
Predicted Functional Partners:
BDCG_09126
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
    
   0.919
BDCG_06956
Phosphate transporter.
    
 
 0.599
GET3
ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]
    
 
 0.591
GET1
Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
    
 
 0.541
BDCG_09233
Protein transporter SEC61 subunit alpha.
    
 
 0.520
BDCG_08518
DNA repair protein.
    
 
 0.514
BDCG_05470
DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.
    
 
 0.512
BDCG_06368
Rad51 domain-containing protein.
    
 
 0.510
BDCG_01892
Meiotic recombination protein DMC1; Belongs to the RecA family.
    
 
 0.510
BDCG_01428
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
   
   0.478
Your Current Organism:
Blastomyces dermatitidis
NCBI taxonomy Id: 559297
Other names: Ajellomyces dermatitidis ER-3, B. dermatitidis ER-3, Blastomyces dermatitidis ER-3
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.