STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BDCG_01554Short chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (328 aa)    
Predicted Functional Partners:
BDCG_05810
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
    
  0.900
BDCG_01984
Stearoyl-CoA desaturase (Delta-9 desaturase); Belongs to the cytochrome b5 family.
    
 0.896
BDCG_06371
Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.
    
 0.896
BDCG_06397
Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
  
 
0.895
BDCG_08202
Enoyl reductase.
    
  0.888
BDCG_08520
Omega-6 fatty acid desaturase (Delta-12 desaturase).
    
  0.883
BDCG_17035
Uncharacterized protein.
    
  0.665
BDCG_04486
Elongation of fatty acids protein.
    
  0.652
BDCG_04732
Elongation of fatty acids protein.
    
  0.652
BDCG_00114
Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
   
 
 0.642
Your Current Organism:
Blastomyces dermatitidis
NCBI taxonomy Id: 559297
Other names: Ajellomyces dermatitidis ER-3, B. dermatitidis ER-3, Blastomyces dermatitidis ER-3
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