STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BDCG_03115Nuclear movement protein nudC. (198 aa)    
Predicted Functional Partners:
BDCG_03178
PLK protein kinase, variant.
    
 0.918
PAC1
Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.
   
 0.909
BDCG_00135
Nuclear distribution protein NudE.
     
 0.817
BDCG_04145
Dynein light intermediate chain, variant.
    
 0.790
BDCG_01425
Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
     
 0.782
BDCG_08126
Dynein heavy chain, cytoplasmic.
    
 0.744
BDCG_07696
BUB protein kinase.
     
 0.737
BDCG_08076
Dynein intermediate chain, cytosolic.
    
 0.705
BDCG_01047
Mitotic spindle assembly checkpoint protein MAD1.
    
  0.705
BDCG_01860
Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).
   
  0.686
Your Current Organism:
Blastomyces dermatitidis
NCBI taxonomy Id: 559297
Other names: Ajellomyces dermatitidis ER-3, B. dermatitidis ER-3, Blastomyces dermatitidis ER-3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.