STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (277 aa)    
Predicted Functional Partners:
BDCG_02239
Adenosine kinase.
  
 0.976
BDCG_08325
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 0.965
BDCG_02397
Adenine phosphoribosyltransferase.
  
 
 0.964
BDCG_04384
Nucleoside diphosphate kinase.
  
 0.957
BDCG_08538
AMP deaminase.
   
 
 0.950
BDCG_08738
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.950
BDCG_00412
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
 0.944
ADK2
GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
  
 
 
0.934
BDCG_02650
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
     
 0.929
BDCG_05154
Ribonucleoside-diphosphate reductase small chain.
     
 0.928
Your Current Organism:
Blastomyces dermatitidis
NCBI taxonomy Id: 559297
Other names: Ajellomyces dermatitidis ER-3, B. dermatitidis ER-3, Blastomyces dermatitidis ER-3
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