STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BDCG_06718RBR-type E3 ubiquitin transferase. (640 aa)    
Predicted Functional Partners:
BDCG_08352
RBR-type E3 ubiquitin transferase.
     
0.698
BDCG_03468
Eukaryotic peptide chain release factor GTP-binding subunit.
   
 
 0.617
BDCG_03110
Uncharacterized protein.
     
 0.576
BDCG_09329
RBR-type E3 ubiquitin transferase.
     
 0.576
BDCG_01656
Ubiquitin-activating enzyme E1 C.
   
 
  0.560
BDCG_09495
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
     
 0.540
BDCG_01004
Uncharacterized protein.
   
 
  0.519
BDCG_05362
Spindle poison sensitivity protein Scp3.
   
 
  0.519
BDCG_08200
E3 ubiquitin-protein ligase HUWE1.
     
 0.495
BDCG_16497
Uncharacterized protein.
     
 0.485
Your Current Organism:
Blastomyces dermatitidis
NCBI taxonomy Id: 559297
Other names: Ajellomyces dermatitidis ER-3, B. dermatitidis ER-3, Blastomyces dermatitidis ER-3
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