STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BDCG_07526Thiamine pyrophosphate enzyme; Belongs to the TPP enzyme family. (697 aa)    
Predicted Functional Partners:
BDCG_02915
Acetolactate synthase I/III small subunit, variant 1.
  
 0.990
BDCG_00341
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.828
BDCG_01929
Branched-chain amino acid aminotransferase.
  
 0.828
BDCG_06433
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 
 0.794
BDCG_08738
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.780
BDCG_03182
Alanine-glyoxylate transaminase/(R)-3-amino-2-methylpropionate-pyruvate transaminase.
  
 
 0.774
BDCG_03491
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.766
BDCG_07979
Peroxisomal targeting signal-1 receptor.
    
 0.765
BDCG_00194
Malic enzyme.
  
 
 0.715
BDCG_05870
Malate dehydrogenase (Oxaloacetate-decarboxylating).
  
 
 0.715
Your Current Organism:
Blastomyces dermatitidis
NCBI taxonomy Id: 559297
Other names: Ajellomyces dermatitidis ER-3, B. dermatitidis ER-3, Blastomyces dermatitidis ER-3
Server load: low (20%) [HD]