STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BDCG_07543RING-type domain-containing protein. (184 aa)    
Predicted Functional Partners:
BDCG_02378
SUMO-conjugating enzyme ubc9; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.655
BDCG_04433
Histone acetyltransferase type B subunit 2.
    
 0.639
BDCG_01023
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.620
BDCG_06486
Histone H2A; Belongs to the histone H2A family.
    
 0.620
BDCG_08642
HLH transcription factor, variant 1.
    
  0.605
BDCG_08641
Uncharacterized protein.
    
  0.605
BDCG_06954
Histone H2A; Belongs to the histone H2A family.
    
 0.599
MDM34
Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
    
  0.598
BDCG_08034
CMGC/CK2 protein kinase; Belongs to the protein kinase superfamily.
    
  0.598
BDCG_16300
Chromo domain-containing protein.
    
 0.588
Your Current Organism:
Blastomyces dermatitidis
NCBI taxonomy Id: 559297
Other names: Ajellomyces dermatitidis ER-3, B. dermatitidis ER-3, Blastomyces dermatitidis ER-3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.