STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BDBG_01513DNA ligase (ATP). (1090 aa)    
Predicted Functional Partners:
BDBG_17946
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.928
BDBG_07791
DNA ligase.
   
 
0.919
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.864
BDBG_01922
Replication factor C subunit 2/4.
   
 0.830
BDBG_00482
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.812
BDBG_00401
ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.
   
 0.804
BDBG_02777
DNA polymerase.
   
 0.779
BDBG_08444
ATP-dependent DNA helicase II subunit 1.
   
 0.774
BDBG_05593
Replication factor C subunit 5.
   
 0.753
BDBG_02669
Replication factor C subunit 3/5.
   
 0.746
Your Current Organism:
Blastomyces gilchristii
NCBI taxonomy Id: 559298
Other names: Ajellomyces dermatitidis SLH#14081, Ajellomyces dermatitidis SLH14081, B. gilchristii SLH14081, Blastomyces dermatitidis SLH14081, Blastomyces gilchristii SLH14081
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.