node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BDBG_01624 | BDBG_02279 | A0A179UBH3 | A0A179UDR0 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | DNA repair protein RAD50. | 0.999 |
BDBG_01624 | BDBG_05091 | A0A179UBH3 | A0A179UMT3 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Exonuclease 1. | 0.985 |
BDBG_01624 | BDBG_05900 | A0A179UBH3 | A0A179UQE0 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | DNA replication ATP-dependent helicase Dna2. | 0.882 |
BDBG_01624 | BDBG_05997 | A0A179UBH3 | A0A179UQQ5 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. | 0.942 |
BDBG_01624 | BDBG_06034 | A0A179UBH3 | A0A179UT82 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | SAE2 domain-containing protein. | 0.865 |
BDBG_01624 | BDBG_06035 | A0A179UBH3 | A0A179UVJ9 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Peroxisomal membrane protein PEX16. | 0.865 |
BDBG_01624 | BDBG_06825 | A0A179UBH3 | A0A179UT78 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | RAD52 DNA repair protein RADC. | 0.839 |
BDBG_01624 | BDBG_08252 | A0A179UBH3 | A0A179V0H9 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.982 |
BDBG_01624 | BDBG_09160 | A0A179UBH3 | A0A179V1V4 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. | 0.961 |
BDBG_01624 | FEN1 | A0A179UBH3 | C5JVG7 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.968 |
BDBG_02279 | BDBG_01624 | A0A179UDR0 | A0A179UBH3 | DNA repair protein RAD50. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.999 |
BDBG_02279 | BDBG_05091 | A0A179UDR0 | A0A179UMT3 | DNA repair protein RAD50. | Exonuclease 1. | 0.876 |
BDBG_02279 | BDBG_05900 | A0A179UDR0 | A0A179UQE0 | DNA repair protein RAD50. | DNA replication ATP-dependent helicase Dna2. | 0.694 |
BDBG_02279 | BDBG_05997 | A0A179UDR0 | A0A179UQQ5 | DNA repair protein RAD50. | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. | 0.885 |
BDBG_02279 | BDBG_06034 | A0A179UDR0 | A0A179UT82 | DNA repair protein RAD50. | SAE2 domain-containing protein. | 0.835 |
BDBG_02279 | BDBG_06035 | A0A179UDR0 | A0A179UVJ9 | DNA repair protein RAD50. | Peroxisomal membrane protein PEX16. | 0.835 |
BDBG_02279 | BDBG_06825 | A0A179UDR0 | A0A179UT78 | DNA repair protein RAD50. | RAD52 DNA repair protein RADC. | 0.918 |
BDBG_02279 | BDBG_08252 | A0A179UDR0 | A0A179V0H9 | DNA repair protein RAD50. | Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. | 0.967 |
BDBG_02279 | BDBG_09160 | A0A179UDR0 | A0A179V1V4 | DNA repair protein RAD50. | Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. | 0.935 |
BDBG_02279 | FEN1 | A0A179UDR0 | C5JVG7 | DNA repair protein RAD50. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.911 |