STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BDBG_08104Aldoxime dehydratase. (359 aa)    
Predicted Functional Partners:
BDBG_03342
Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...]
  
  
 0.710
BDBG_04462
Pyridoxine kinase.
   
 
 0.690
BDBG_08554
Protein Arg-6, mitochondrial; In the N-terminal section; belongs to the acetylglutamate kinase family.
     
 0.668
BDBG_01562
RalA-binding protein 1.
   
 
 0.631
BDBG_02032
Biotin synthetase.
  
  
 0.457
BDBG_05604
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
     
 0.456
BDBG_01707
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.450
BDBG_16209
Importin N-terminal domain-containing protein.
  
  
 0.434
BDBG_03731
Ubiquitin-like 1-activating enzyme E1 A.
  
  
 0.434
uba4
Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
  
  
 0.434
Your Current Organism:
Blastomyces gilchristii
NCBI taxonomy Id: 559298
Other names: Ajellomyces dermatitidis SLH#14081, Ajellomyces dermatitidis SLH14081, B. gilchristii SLH14081, Blastomyces dermatitidis SLH14081, Blastomyces gilchristii SLH14081
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