STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (473 aa)    
Predicted Functional Partners:
BDBG_04410
Dynein heavy chain, cytoplasmic.
    
 0.996
BDBG_08078
Nuclear distribution protein NudE.
    
 
 0.949
BDBG_05683
Lysophospholipase.
     
 0.920
BDBG_02011
Putative phospholipase.
     
 0.919
BDBG_02440
Nuclear movement protein nudC.
   
 0.908
BDBG_04237
Dynein intermediate chain, cytosolic.
   
 0.905
BDBG_02447
Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.
     
  0.900
BDBG_07704
MBOAT family protein, variant 1; Belongs to the membrane-bound acyltransferase family.
     
  0.900
BDBG_02245
Uncharacterized protein.
    
 0.881
BDBG_03243
Dynactin.
    
 0.830
Your Current Organism:
Blastomyces gilchristii
NCBI taxonomy Id: 559298
Other names: Ajellomyces dermatitidis SLH#14081, Ajellomyces dermatitidis SLH14081, B. gilchristii SLH14081, Blastomyces dermatitidis SLH14081, Blastomyces gilchristii SLH14081
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