STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TERG_118093-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (281 aa)    
Predicted Functional Partners:
TERG_01871
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.980
TERG_01521
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.976
TERG_07659
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.974
TERG_11810
HMG_CoA_synt_N domain-containing protein.
 
     0.947
TERG_12462
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 
 0.945
TERG_12461
HPIH domain-containing protein.
  
 
 0.945
TERG_03476
Pyruvate carboxyltransferase domain-containing protein.
     
 0.917
TERG_01052
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
    
 0.913
TERG_06371
Acetoacetate-CoA ligase.
   
 
 0.910
TERG_07451
Acetoacetate-CoA ligase.
   
 
 0.910
Your Current Organism:
Trichophyton rubrum
NCBI taxonomy Id: 559305
Other names: T. rubrum CBS 118892, Trichophyton rubrum CBS 118892
Server load: low (28%) [HD]