STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRM5tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (349 aa)    
Predicted Functional Partners:
TERG_02121
RPOL4c domain-containing protein.
 
  
   0.932
TERG_08721
Uncharacterized protein.
 
      0.848
TERG_02087
Uncharacterized protein.
 
      0.807
TERG_01792
RPA_C domain-containing protein.
    
 0.711
TERG_04692
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.690
TERG_00156
ERCC4 domain-containing protein.
    
  0.674
TERG_04518
Histone acetyltransferase type B subunit 2.
    
 0.649
TERG_07476
ERCC4 domain-containing protein.
    
  0.622
TERG_01881
Uncharacterized protein.
    
  0.617
TERG_06150
Deoxyuridine 5'-triphosphate nucleotidohydrolase.
    
  0.617
Your Current Organism:
Trichophyton rubrum
NCBI taxonomy Id: 559305
Other names: T. rubrum CBS 118892, Trichophyton rubrum CBS 118892
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.