STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TERG_04980Exonuclease domain-containing protein. (306 aa)    
Predicted Functional Partners:
TERG_04981
Uncharacterized protein.
 
 
    0.929
PAN3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]
    
 0.919
TERG_02452
WD_REPEATS_REGION domain-containing protein.
   
  0.889
TERG_12335
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.837
TERG_00192
RNA helicase.
  
 0.836
TERG_00248
Brix domain-containing protein.
   
   0.833
TERG_03204
60S ribosomal protein L7.
   
 0.792
TERG_04979
Uncharacterized protein.
 
    
 0.778
TERG_08590
Uncharacterized protein.
   
   0.772
TERG_01968
RRM domain-containing protein.
   
 0.765
Your Current Organism:
Trichophyton rubrum
NCBI taxonomy Id: 559305
Other names: T. rubrum CBS 118892, Trichophyton rubrum CBS 118892
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.