STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BU52_03990Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)    
Predicted Functional Partners:
BU52_24035
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.890
BU52_03125
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.867
BU52_21790
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.848
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.807
BU52_07015
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.757
BU52_08675
Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.
   
 
  0.757
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.713
BU52_06330
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.709
BU52_12000
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.709
BU52_27745
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.693
Your Current Organism:
Streptomyces toyocaensis
NCBI taxonomy Id: 55952
Other names: S. toyocaensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.